Tjp1 - tight junction protein 1 Gene
Also Known as ZO-1
生物種: Rattus norvegicus
Summary
Enables protein C-terminus binding activity. Involved in several processes, including cellular response to glucose stimulus; negative regulation of vascular permeability; and response to lipopolysaccharide. Located in bicellular tight junction; cytoplasm; and gap junction. Biomarker of several diseases, including brain ischemia; cholestasis; peptic esophagitis; perinatal necrotizing enterocolitis; and uveitis. Orthologous to human TJP1 (tight junction protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Tjp1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001106266.1 | NP_001099736.1 | tight junction protein ZO-1 |
| Molecular Function GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| enables beta-catenin binding |
IPI
IPI: Inferred from physical interaction
|
12960056 | RGD |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
16617054 | RGD |
| enables transmembrane transporter binding |
IPI
IPI: Inferred from physical interaction
|
15980428 | RGD |
| Biological Process GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| involved in cellular response to glucose stimulus |
IEP
IEP: Inferred from expression pattern
|
16567508 | RGD |
| involved in negative regulation of vascular permeability |
IEP
IEP: Inferred from expression pattern
|
20137299 | RGD |
| involved in response to ethanol |
IEP
IEP: Inferred from expression pattern
|
17515855 | RGD |
| involved in response to lipopolysaccharide |
IEP
IEP: Inferred from expression pattern
|
17515855 | RGD |
| involved in response to magnetism |
IEP
IEP: Inferred from expression pattern
|
20137299 | RGD |
| involved in response to xenobiotic stimulus |
IEP
IEP: Inferred from expression pattern
|
18360096 | RGD |
| Cellular Component GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| located in bicellular tight junction |
IDA
IDA: Inferred from direct assay
|
17899156 | RGD |
| located in cell-cell junction |
IDA
IDA: Inferred from direct assay
|
25486565 | RGD |
| located in gap junction |
IDA
IDA: Inferred from direct assay
|
29021339 | RGD |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
tight junction protein ZO-1 |
|
|