Gpr139 - G protein-coupled receptor 139 Gene

Rattus norvegicus

Gene ID: 293545 | Gene type: protein coding

About Gpr139

Primary_assembly 1: 173,481,583-173,522,451 reverse strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 335 orthologues and 1 paralogue. Restricted expression toward (RPKM 8.4).

Summary

Predicted to enable identical protein binding activity and neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to act upstream of or within Phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Orthologous to human GPR139 (G protein-coupled receptor 139). [provided by Alliance of Genome Resources, Apr 2022]

Gpr139 Products(1)

mRNA	Protein	Name
NM_001024241.2	NP_001019412.1	probable G-protein coupled receptor 139

Gpr139 Protein Structure

7tmA_GPR139

0
100
200
300
345 a.a.

Protein Preferred Names

Protein Names

probable G-protein coupled receptor 139

g(q)-coupled orphan receptor GPRg1

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-132228	Zelatriazin	Agonist	99.89%	Phase 2

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-19838	JNJ-63533054	Agonist	99.90%	Unkown
HY-128057	NCRW0005-F05	Antagonist	≥99.0%	Unkown
HY-119168	LP-471756	Antagonist	99.69%	Unkown
HY-101777	TC-O 9311	Agonist	99.70%	Unkown
HY-149651	GPR139 agonist-2	Agonist	99.80%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gpr139	NCBI	NCBI:124274

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