Slc26a4 - solute carrier family 26 member 4 Gene

Also Known as Pds

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29440

Summary

Enables chloride transmembrane transporter activity and iodide transmembrane transporter activity. Involved in inorganic anion transport. Located in apical plasma membrane. Human ortholog(s) of this gene implicated in Pendred Syndrome; autosomal recessive nonsyndromic deafness 4; and goiter. Orthologous to human SLC26A4 (solute carrier family 26 member 4). [provided by Alliance of Genome Resources, Apr 2022]

Slc26a4 Products (1)

mRNA Protein Name
NM_019214.1 NP_062087.1 pendrin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chloride transmembrane transporter activity IDA
IDA: Inferred from direct assay
12107249 RGD
enables chloride:bicarbonate antiporter activity IDA
IDA: Inferred from direct assay
11208611 RGD
enables iodide transmembrane transporter activity IDA
IDA: Inferred from direct assay
12107249 RGD
Biological Process GO Annotation Evidence References Source
involved in inorganic anion transport IDA
IDA: Inferred from direct assay
12107249 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
11208611 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
26791486 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pendrin

  • Pendred syndrome homolog

  • sodium-independent chloride/iodide transporter

  • solute carrier family 26 (anion exchanger), member 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-159706 S9-A13 Inhibitor / Unkown
HY-168735 SLC26A4-IN-1 Inhibitor 99.01% Unkown
HY-184897 YS-01 Inhibitor / Unkown
HY-184898 PDSinh-C01 Inhibitor / Unkown
HY-RS13138 SLC26A4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-Y1269D Ammonium chloride, for molecular biology / Unkown
HY-RS21256 Slc26a4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27775 Slc26a4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc26a4 NCBI NCBI:5172