Pla2g2a - phospholipase A2 group IIA Gene

Also Known as sPLA2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29692

Summary

Enables calcium-dependent Phospholipase A2 activity. Involved in phospholipid metabolic process. Located in perinuclear region of cytoplasm and secretory granule. Human ortholog(s) of this gene implicated in cholecystolithiasis; colorectal cancer; gastroesophageal reflux disease; and human immunodeficiency virus infectious disease. Orthologous to human PLA2G2A (Phospholipase A2 group IIA). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g2a Products (1)

mRNA Protein Name
NM_031598.3 NP_113786.3 phospholipase A2, membrane associated precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium-dependent phospholipase A2 activity IDA
IDA: Inferred from direct assay
9487151 RGD
Biological Process GO Annotation Evidence References Source
involved in phospholipid metabolic process IDA
IDA: Inferred from direct assay
9487151 RGD
Cellular Component GO Annotation Evidence References Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
11034413 RGD
located in secretory granule IDA
IDA: Inferred from direct assay
9487151 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipase A2, membrane associated

  • GIIC sPLA2

  • eted enzyme type IIA phospholipase A2

  • group IIA phospholipase A2

  • phosphatidylcholine 2-acylhydrolase 2A

  • phospholipase A2, group IIA (platelets, synovial fluid)

  • platelet phospholipase A2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10621 PLA2G2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17567 Pla2g2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24027 Pla2g2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g2a NCBI NCBI:5320