Foxp1 - forkhead box P1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 297480

Summary

Enables transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to ionomycin; negative regulation of cell growth involved in cardiac muscle cell development; and positive regulation of hydrogen peroxide-induced cell death. Located in cytoplasm and nucleus. Biomarker of hepatocellular carcinoma; lung adenocarcinoma; and trichostrongyloidiasis. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; congenital heart disease; esophagus adenocarcinoma; intellectual disability-severe speech delay-mild dysmorphism syndrome; and peritonitis. Orthologous to human FOXP1 (forkhead box P1). [provided by Alliance of Genome Resources, Apr 2022]

Foxp1 Products (1)

mRNA Protein Name
NM_001034131.2 NP_001029303.1 forkhead box protein P1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to tumor necrosis factor IEP
IEP: Inferred from expression pattern
26842647 RGD
involved in forebrain development IEP
IEP: Inferred from expression pattern
18561326 RGD
involved in negative regulation of cell growth involved in cardiac muscle cell development IMP
IMP: Inferred from mutant phenotype
26333362 RGD
involved in positive regulation of hydrogen peroxide-mediated programmed cell death IMP
IMP: Inferred from mutant phenotype
26333362 RGD
involved in response to testosterone IEP
IEP: Inferred from expression pattern
25247470 RGD
involved in striatum development IEP
IEP: Inferred from expression pattern
12815709 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

forkhead box protein P1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05073 FOXP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19683 Foxp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26176 Foxp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Foxp1 NCBI NCBI:27086