Mapk12 - mitogen-activated protein kinase 12 Gene

Also Known as Erk6; Sapk3; Prkm12; P38gamma

Species: Mus musculus

Gene Type: protein coding
Gene ID: 29857

About Mapk12

Chromosome 15: 89,014,787-89,024,906 reverse strand.GRCm39:CM001008.3

This gene has 7 transcripts (splice variants), 288 orthologues, 19 paralogues and is associated with 1 phenotype. Broad expression in cerebellum adult (RPKM 12.5), bladder adult (RPKM 9.4) and 25 other tissues.

Summary

Predicted to enable ATP binding activity; MAP kinase activity; and magnesium ion binding activity. Predicted to be involved in several processes, including intracellular signal transduction; myoblast differentiation; and peptidyl-serine phosphorylation. Predicted to act upstream of or within phosphorylation. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in cap mesenchyme; lung mesenchyme; metanephros; and olfactory epithelium. Orthologous to human MAPK12 (mitogen-activated protein kinase 12). [provided by Alliance of Genome Resources, Apr 2022]

Mapk12 Products (5)

mRNA Protein Name
NM_001403020.1 NP_001389949.1 mitogen-activated protein kinase 12 isoform 3
NM_001403021.1 NP_001389950.1 mitogen-activated protein kinase 12 isoform 4
NM_013871.4 NP_038899.1 mitogen-activated protein kinase 12 isoform 1
NM_001403022.1 NP_001389951.1 mitogen-activated protein kinase 12 isoform 4
NM_001403019.1 NP_001389948.1 mitogen-activated protein kinase 12 isoform 2

Mapk12 Protein Structure

STKc_p38gamma

STKc_p38gamma: cd07880 (10 - 352)

  • 0
  • 100
  • 200
  • 300
  • 367 a.a.
Protein Preferred Names Protein Names

mitogen-activated protein kinase 12

  • ERK-6

  • MAP kinase 12

  • MAP kinase p38 gamma

  • MAPK 12

  • extracellular signal-regulated kinase 6

  • mitogen-activated protein kinase p38 gamma

  • stress-activated protein kinase 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N2441 Methylophiopogonone A Inhibitor 99.94% Unkown
HY-186241 NuP-3 Inhibitor / Unkown
HY-RS08101 MAPK12 Human Pre-designed siRNA Set A / Unkown
HY-RS08102 Mapk12 Mouse Pre-designed siRNA Set A / Unkown
HY-RS08103 Mapk12 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapk12 NCBI NCBI:6300