Clic4 - chloride intracellular channel 4 (mitochondrial) Gene

Also Known as TU-74; mc3s5; D0Jmb3; mtCLIC

Species: Mus musculus

Gene Type: protein coding
Gene ID: 29876

Summary

Predicted to enable Chloride Channel activity. Involved in keratinocyte differentiation. Acts upstream of or within several processes, including endothelial cell morphogenesis; vacuolar acidification; and vasculature development. Located in mitochondrion. Is expressed in brain; skin; and spleen. Orthologous to human CLIC4 (chloride intracellular channel 4). [provided by Alliance of Genome Resources, Apr 2022]

Clic4 Products (1)

mRNA Protein Name
NM_013885.2 NP_038913.1 chloride intracellular channel protein 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within angiogenesis IMP
IMP: Inferred from mutant phenotype
19197003 MGI
acts upstream of or within branching morphogenesis of an epithelial tube IMP
IMP: Inferred from mutant phenotype
19197003 MGI
acts upstream of or within endothelial cell morphogenesis IMP
IMP: Inferred from mutant phenotype
19197003 MGI
acts upstream of or within fertilization IMP
IMP: Inferred from mutant phenotype
19197003 MGI
involved in keratinocyte differentiation IMP
IMP: Inferred from mutant phenotype
17636002 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
19197003 MGI
acts upstream of or within retina vasculature morphogenesis in camera-type eye IMP
IMP: Inferred from mutant phenotype
19197003 MGI
acts upstream of or within vacuolar acidification IMP
IMP: Inferred from mutant phenotype
19197003 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
10593946 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chloride intracellular channel protein 4

  • mc3s5/mtCLIC

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02806 CLIC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20381 Clic4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26891 Clic4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clic4 NCBI NCBI:25932