Cbx5 - chromobox 5 Gene

Predicted to enable several functions, including histone deacetylase binding activity; identical protein binding activity; and methylated histone binding activity. Predicted to be involved in cellular response to DNA damage stimulus; chromatin organization; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription, DNA-templated. Predicted to be located in chromocenter; chromosome; and nuclear lumen. Predicted to be part of nucleoplasm; ribonucleoprotein complex; and transcription repressor complex. Predicted to be active in pericentric heterochromatin. Predicted to colocalize with PML body. Orthologous to human CBX5 (chromobox 5). [provided by Alliance of Genome Resources, Apr 2022]