Kdm4b - lysine demethylase 4B Gene
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 301128
Summary
Predicted to enable histone H3-methyl-lysine-36 demethylase activity and histone H3-methyl-lysine-9 demethylase activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within histone H3-K36 demethylation; histone H3-K9 demethylation; and negative regulation of histone H3-K9 trimethylation. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach Cancer. Orthologous to human KDM4B (lysine demethylase 4B). [provided by Alliance of Genome Resources, Apr 2022]
Kdm4b Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001044236.3 | NP_001037701.2 | lysine-specific demethylase 4B isoform 1 |
| NM_001395633.1 | NP_001382562.1 | lysine-specific demethylase 4B isoform 2 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
lysine-specific demethylase 4B |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(9)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-104048 | QC6352 | Inhibitor | 99.13% | Unkown |
| HY-12725 | ML324 | Inhibitor | 98.35% | Unkown |
| HY-148807 | Zavondemstat | 99.29% | Unkown | |
| HY-101799 | NCGC00244536 | Inhibitor | 99.70% | Unkown |
| HY-110154 | NSC636819 | 98.90% | Unkown | |
| HY-RS07214 | KDM4B Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-173135 | PROTAC KDM4 degrader-1 | / | Unkown | |
| HY-RS17132 | Kdm4b Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS23577 | Kdm4b Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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