Cbx8 - chromobox 8 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 303731

Summary

Predicted to enable methylated histone binding activity; single-stranded RNA binding activity; and ubiquitin-protein transferase activator activity. Involved in several processes, including cellular response to hydrogen peroxide; positive regulation of DNA repair; and positive regulation of Collagen biosynthetic process. Predicted to be located in heterochromatin and nucleoplasm. Predicted to be part of PRC1 complex. Orthologous to human CBX8 (chromobox 8). [provided by Alliance of Genome Resources, Apr 2022]

Cbx8 Products (1)

mRNA Protein Name
NM_001034078.1 NP_001029250.1 chromobox protein homolog 8

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to hydrogen peroxide IEP
IEP: Inferred from expression pattern
23572236 RGD
involved in positive regulation of DNA repair IMP
IMP: Inferred from mutant phenotype
23572236 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
23572236 RGD
involved in positive regulation of collagen biosynthetic process IMP
IMP: Inferred from mutant phenotype
23572236 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chromobox protein homolog 8

  • chromobox homolog 8 (Pc class homolog, Drosophila)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-141716 SW2_110A Inhibitor 99.19% Unkown
HY-181089 CBX2-IN-1 Inhibitor / Unkown
HY-RS02015 CBX8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19122 Cbx8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25612 Cbx8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbx8 NCBI NCBI:57332