F12 - coagulation factor XII Gene

Also Known as HAF

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 306761

Summary

Predicted to enable serine-type endopeptidase activity. Involved in blood coagulation. Located in extracellular space. Used to study hyperhomocysteinemia. Human ortholog(s) of this gene implicated in angioedema (multiple); cerebrovascular disease (multiple); factor XII deficiency; and myocardial infarction. Orthologous to human F12 (coagulation factor XII). [provided by Alliance of Genome Resources, Apr 2022]

F12 Products (1)

mRNA Protein Name
NM_001014006.1 NP_001014028.1 coagulation factor XII precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
2324612 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coagulation factor XII

  • factor XII

  • hageman factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150287 Insulin-Transferrin-Selenium, 100X / Unkown
HY-W760183 EM12-SO2F 99.15% Unkown
HY-130260 KRAS inhibitor-4 Inhibitor / Unkown
HY-RS03479 CYP4F12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04627 F12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W143313 1,2-Heptanediol 98.0% Unkown
HY-RS16842 F12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23284 F12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990150 Anti-Mouse TSLP Antibody (28F12) Inhibitor 98.395% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F12 NCBI NCBI:2161