Gpt2 - glutamic--pyruvic transaminase 2 Gene
Also Known as ALT2; Cc2-5
Species: Rattus norvegicus
Summary
Predicted to enable L-alanine:2-oxoglutarate aminotransferase activity. Involved in several processes, including cellular response to Insulin stimulus; positive regulation of gluconeogenesis; and response to testosterone. Located in extracellular space and mitochondrion. Biomarker of type 2 diabetes mellitus. Orthologous to human GPT2 (glutamic--pyruvic transaminase 2). [provided by Alliance of Genome Resources, Apr 2022]
Gpt2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001012057.2 | NP_001012057.1 | alanine aminotransferase 2 |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in cellular response to insulin stimulus |
IEP
IEP: Inferred from expression pattern
|
25865565 | RGD |
| involved in gluconeogenesis |
IMP
IMP: Inferred from mutant phenotype
|
25865565 | RGD |
| involved in response to starvation |
IEP
IEP: Inferred from expression pattern
|
25865565 | RGD |
| involved in response to testosterone |
IEP
IEP: Inferred from expression pattern
|
22167351 | RGD |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in extracellular space |
IDA
IDA: Inferred from direct assay
|
19085960 | RGD |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
alanine aminotransferase 2 |
|
Recombinant Gpt2 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P75797 | GPT2 Protein, Rat (sf9, His) | NP_001012057.1 (M1-S522) | ≥ 95%, as determined by reducing SDS-PAGE. |