Rictor - RPTOR independent companion of MTOR, complex 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 310131

Summary

Predicted to enable protein kinase binding activity; protein serine/threonine kinase activator activity; and ribosome binding activity. Involved in positive regulation of endothelial cell proliferation; positive regulation of protein kinase B signaling; and regulation of phosphorylation. Predicted to be part of TORC2 complex. Orthologous to human RICTOR (RPTOR independent companion of mTOR complex 2). [provided by Alliance of Genome Resources, Apr 2022]

Rictor Products (3)

mRNA Protein Name
XM_039103527.1 XP_038959455.1 rapamycin-insensitive companion of mTOR isoform X1
XM_008760807.2 XP_008759029.2 rapamycin-insensitive companion of mTOR isoform X2
XM_039103528.1 XP_038959456.1 rapamycin-insensitive companion of mTOR isoform X3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of endothelial cell proliferation IMP
IMP: Inferred from mutant phenotype
17110594 RGD
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
17110594 RGD
involved in regulation of phosphorylation IMP
IMP: Inferred from mutant phenotype
17110594 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rapamycin-insensitive companion of mTOR

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-19307 SB-273005 99.94% Phase 1

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122022 JR-AB2-011 Inhibitor 98.15% Unkown
HY-RS11969 RICTOR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17350 Rictor Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23804 Rictor Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rictor NCBI NCBI:253260