Nrf1 - nuclear respiratory factor 1 Gene

Also Known as Nfe2l1_retired

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 312195

Summary

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. Confusion has occurred in bibliographic databases for genes in the "nuclear respiratory factor" and "nuclear factor (erythroid-derived 2)-like" families due to a shared symbol or alias of Nrf1. [provided by RefSeq, Jul 2008]

Nrf1 Products (1)

mRNA Protein Name
NM_001100708.1 NP_001094178.1 nuclear respiratory factor 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
9501001 RGD
involved in response to electrical stimulus IDA
IDA: Inferred from direct assay
9575220 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
15994367 RGD
involved in response to folic acid IEP
IEP: Inferred from expression pattern
17709439 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
18078825 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
18062988 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
33310031 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear respiratory factor 1

  • NRF-1

  • alpha palindromic-binding protein

  • alpha-pal

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-129225 WRR139 Inhibitor 99.71% Unkown
HY-149127 Rosolutamide 99.03% Unkown
HY-RS09567 NRF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-125535 OSU-53 / Unkown
HY-184160 Mcl1 Degrader-1 / Unkown
HY-RS09244 NFE2L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17333 Nrf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21165 Nfe2l1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23788 Nrf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nrf1 NCBI NCBI:4899