Smug1 - single-strand-selective monofunctional uracil-DNA glycosylase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 315344

Summary

Enables oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity and single-strand selective uracil DNA N-glycosylase activity. Involved in base-excision repair. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Orthologous to human SMUG1 (single-strand-selective monofunctional uracil-DNA glycosylase 1). [provided by Alliance of Genome Resources, Apr 2022]

Smug1 Products (1)

mRNA Protein Name
NM_177934.3 NP_808795.1 single-strand selective monofunctional uracil-DNA glycosylase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity IDA
IDA: Inferred from direct assay
12718542 RGD
enables single-strand selective uracil DNA N-glycosylase activity IDA
IDA: Inferred from direct assay
12718543 RGD
enables uracil DNA N-glycosylase activity IDA
IDA: Inferred from direct assay
12718542 RGD
Biological Process GO Annotation Evidence References Source
involved in DNA repair IDA
IDA: Inferred from direct assay
12718542 RGD
involved in base-excision repair IDA
IDA: Inferred from direct assay
12718543 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

single-strand selective monofunctional uracil-DNA glycosylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-184013 SU0617 Inhibitor / Unkown
HY-RS13458 SMUG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20492 Smug1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27000 Smug1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smug1 NCBI NCBI:23583