Iqcb1 - IQ calmodulin-binding motif containing 1 Gene

Also Known as NPHP5; 6820449I09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 320299

Summary

Predicted to enable Calmodulin binding activity and enzyme binding activity. Involved in cilium assembly. Located in photoreceptor connecting cilium and photoreceptor outer segment. Is expressed in several structures, including heart ventricle; metanephros; retina; and telencephalon ventricular layer. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Senior-Loken syndrome; nephronophthisis; and retinitis pigmentosa 3. Orthologous to human IQCB1 (IQ motif containing B1). [provided by Alliance of Genome Resources, Apr 2022]

Iqcb1 Products (1)

mRNA Protein Name
NM_177128.4 NP_796102.2 IQ calmodulin-binding motif-containing protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21565611 MGI
Biological Process GO Annotation Evidence References Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
21565611 MGI
Cellular Component GO Annotation Evidence References Source
located in photoreceptor connecting cilium IDA
IDA: Inferred from direct assay
15723066 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
15723066 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

IQ calmodulin-binding motif-containing protein 1

Iqcb1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Iqcb1 Q8BP00 Cep290 Mus musculus Q6A078
Anti Tag CoIP
21565611
Intra
Iqcb1 Q8BP00 Rpgrip1l Mus musculus Q8CG73
Anti Tag CoIP
21565611
Intra
Iqcb1 Q8BP00 Atxn10 Mus musculus P28658
Anti Tag CoIP
21565611
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06875 IQCB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22576 Iqcb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29094 Iqcb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Iqcb1 NCBI NCBI:9657