Il19 - interleukin 19 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 329244

Summary

Predicted to enable cytokine activity. Involved in negative regulation of low-density lipoprotein particle clearance. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway; positive regulation of intrinsic apoptotic signaling pathway; and Reactive Oxygen Species metabolic process. Predicted to be located in extracellular space. Orthologous to human IL19 (interleukin 19). [provided by Alliance of Genome Resources, Apr 2022]

Il19 Products (2)

mRNA Protein Name
NM_001009940.2 NP_001009940.1 interleukin-19 isoform 1 precursor
NM_001355135.1 NP_001342064.1 interleukin-19 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within interleukin-6 production IDA
IDA: Inferred from direct assay
12370360 MGI
acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway IDA
IDA: Inferred from direct assay
23468852 MGI
involved in negative regulation of low-density lipoprotein particle clearance IMP
IMP: Inferred from mutant phenotype
28257760 MGI
acts upstream of or within positive regulation of apoptotic signaling pathway IDA
IDA: Inferred from direct assay
12370360 MGI
acts upstream of or within positive regulation of intrinsic apoptotic signaling pathway IGI
IGI: Inferred from genetic interaction
23468852 MGI
acts upstream of or within reactive oxygen species metabolic process IDA
IDA: Inferred from direct assay
12370360 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-19

  • IL-19

Recombinant Il19 Proteins

Cat. No. Product Name Accession Purity
HY-P7213 IL-19 Protein, Mouse Q8CJ70 (L25-A176) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700196AF Animal-Free IL-19 Protein, Mouse (His) Q8CJ70 (L25-A176) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06712 IL19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174629 Human IL19 mRNA / Unkown
HY-RS17267 Il19 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23721 Il19 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992240 Anti-IL-19 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il19 NCBI NCBI:29949