Cecr2 - CECR2, histone acetyl-lysine reader Gene

Mus musculus

Also known as Gtl4; 2610101O16Rik; 2810409N01Rik

Gene ID: 330409 | Gene type: protein coding

About Cecr2

Chromosome 6: 120,643,330-120,748,151 forward strand.GRCm39:CM000999.3

This gene has 8 transcripts (splice variants), 156 orthologues, 11 paralogues and is associated with 24 phenotypes. Ubiquitous expression in testis adult (RPKM 4.5), CNS E11.5 (RPKM 4.) and 23 other tissues.

Summary

Predicted to enable ATP-dependent chromatin remodeler activity. Acts upstream of or within inner ear development; primary neural tube formation; and single fertilization. Located in euchromatin. Part of ISWI-type complex. Is expressed in several structures, including extraembryonic component; genitourinary system; and olfactory epithelium. Used to study anencephaly. Orthologous to human CECR2 (CECR2 histone acetyl-lysine reader). [provided by Alliance of Genome Resources, Apr 2022]

Cecr2 Products(2)

mRNA	Protein	Name
NM_001368706.1	NP_001355635.1	chromatin remodeling regulator CECR2 isoform 2
NM_001128151.2	NP_001121623.1	chromatin remodeling regulator CECR2 isoform 1

Cecr2 Protein Structure

Bromo_gcn5_like

PHA03247

0
300
600
900
1200
1453 a.a.

Protein Preferred Names

Protein Names

chromatin remodeling regulator CECR2

cat eye syndrome critical region protein 2 homolog

cat eye syndrome chromosome region, candidate 2 homolog

gene trap locus 4

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-110374	NVS-CECR2-1	Inhibitor	99.40%	Unkown
HY-112610	CF53	Inhibitor	99.78%	Unkown
HY-114205A	TP-238 hydrochloride	Inhibitor	≥99.0%	Unkown
HY-114205	TP-238	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cecr2	NCBI	NCBI:27443

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