Egfl7 - EGF-like domain 7 Gene

Also Known as Zneu1; VE-statin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 353156

Summary

Enables Notch binding activity. Acts upstream of or within negative regulation of cell migration and vasculogenesis. Located in extracellular space. Is expressed in several structures, including cardiovascular system; gonad; hemolymphoid system gland; retina layer; and yolk sac. Orthologous to human EGFL7 (EGF like domain multiple 7). [provided by Alliance of Genome Resources, Apr 2022]

Egfl7 Products (4)

mRNA Protein Name
NM_001164564.2 NP_001158036.2 epidermal growth factor-like protein 7 isoform 1 precursor
NM_178444.5 NP_848538.4 epidermal growth factor-like protein 7 isoform 1 precursor
NM_198724.3 NP_942017.3 epidermal growth factor-like protein 7 isoform 1 precursor
NM_198725.3 NP_942018.3 epidermal growth factor-like protein 7 isoform 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables Notch binding IPI
IPI: Inferred from physical interaction
20947685 MGI
Biological Process GO Annotation Evidence References Source
involved in blood vessel development IEP
IEP: Inferred from expression pattern
15085134 MGI
acts upstream of or within negative regulation of smooth muscle cell migration IDA
IDA: Inferred from direct assay
14592969 MGI
acts upstream of smooth muscle cell migration IDA
IDA: Inferred from direct assay
14592969 MGI
involved in vasculogenesis IEP
IEP: Inferred from expression pattern
15162510 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
15162510 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
14592969 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

epidermal growth factor-like protein 7

  • EGF-like protein 7

  • NEU1 protein

  • NOTCH4-like protein

  • multiple EGF-like domains protein 7

  • multiple epidermal growth factor-like domains protein 7

  • vascular endothelial statin

Recombinant Egfl7 Proteins

Cat. No. Product Name Accession Purity
HY-P75731 EGFL7/VE-Statin Protein, Mouse (sf9, His) Q9QXT5-1 (E22-L275) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99215 Parsatuzumab Modulator 97.94% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04206 EGFL7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18061 Egfl7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24536 Egfl7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Egfl7 NCBI NCBI:51162