Vegfd - vascular endothelial growth factor D Gene

Also Known as Figf; Vegf-d

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360457

Summary

Enables vascular endothelial growth factor receptor binding activity. Involved in several processes, including positive regulation of interleukin-6 production; regulation of vascular endothelial growth factor receptor signaling pathway; and response to interleukin-1. Predicted to be located in extracellular space. Orthologous to human VEGFD (vascular endothelial growth Factor D). [provided by Alliance of Genome Resources, Apr 2022]

Vegfd Products (1)

mRNA Protein Name
NM_031761.2 NP_113949.2 vascular endothelial growth factor D precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables vascular endothelial growth factor receptor binding IMP
IMP: Inferred from mutant phenotype
11683876 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of interleukin-6 production IMP
IMP: Inferred from mutant phenotype
17404025 RGD
involved in regulation of vascular endothelial growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
11683876 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
17289933 RGD
involved in response to interleukin-1 IEP
IEP: Inferred from expression pattern
17929249 RGD
involved in vascular endothelial growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
11683876 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vascular endothelial growth factor D

  • c-fos-induced growth factor

Recombinant Vegfd Proteins

Cat. No. Product Name Accession Purity
HY-P73475 VEGF-D Protein, Rat (HEK293, Fc) O35251 (F94-R210) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15638 VEGFD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174507 Human VEGFD mRNA / Unkown
HY-RS18414 Vegfd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24895 Vegfd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P9920A Ramucirumab (anti-VEGFR) Antagonist 99.9% Unkown
HY-P991626 VGX200 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vegfd NCBI NCBI:2277