Glrx5 - glutaredoxin 5 Gene

Also Known as RGD1308383

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362776

Summary

Predicted to enable glutathione oxidoreductase activity; iron-sulfur cluster binding activity; and metal ion binding activity. Predicted to be involved in [2Fe-2S] cluster assembly; protein maturation by [2Fe-2S] cluster transfer; and protein maturation by [4Fe-4S] cluster transfer. Located in dendrite; neuronal cell body; and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive pyridoxine-refractory sideroblastic anemia 3. Orthologous to human GLRX5 (glutaredoxin 5). [provided by Alliance of Genome Resources, Apr 2022]

Glrx5 Products (1)

mRNA Protein Name
NM_001108722.1 NP_001102192.1 glutaredoxin-related protein 5, mitochondrial

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
20620191 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
20620191 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutaredoxin-related protein 5, mitochondrial

  • glutaredoxin 5 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05499 GLRX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22529 Glrx5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29049 Glrx5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Glrx5 NCBI NCBI:51218