Il27 - interleukin 27 Gene

Also Known as RGD1561420

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 365368

Summary

Predicted to enable interleukin-27 receptor binding activity. Involved in response to bacterium. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and pulmonary tuberculosis. Orthologous to human IL27 (interleukin 27). [provided by Alliance of Genome Resources, Apr 2022]

Il27 Products (2)

mRNA Protein Name
XM_039101198.1 XP_038957126.1 interleukin-27 subunit alpha isoform X1
XM_344962.9 XP_344963.6 interleukin-27 subunit alpha isoform X2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in response to Gram-positive bacterium IEP
IEP: Inferred from expression pattern
16288719 RGD
involved in response to bacterium IEP
IEP: Inferred from expression pattern
16288719 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
16288719 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-27 subunit alpha

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990024 Casdozokitug Inhibitor 96.49% Phase 2

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-151508 Diamino lipid DAL4 / Unkown
HY-RS06746 IL27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06747 IL27RA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08889 MYDGF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174612 Human IL27RA mRNA / Unkown
HY-174613 Human IL27 mRNA / Unkown
HY-RS17022 Ebi3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17036 Il27 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20169 Il27ra Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23480 Il27 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26673 Il27ra Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990215 Anti-Mouse IL-27 p28 Antibody (MM27.7B1) Inhibitor 95.00% Unkown
HY-P992246 Anti-IL-27RA Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il27 NCBI NCBI:246778