Rac2 - Rac family small GTPase 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 366957

Summary

Predicted to enable several functions, including GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in actin Cytoskeleton organization and bone resorption. Predicted to be located in several cellular components, including cytosol; lamellipodium; and nuclear envelope. Predicted to be active in several cellular components, including cell cortex; cytoplasmic vesicle; and Cytoskeleton. Predicted to colocalize with actin filament. Human ortholog(s) of this gene implicated in immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis; immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia; and immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia. Orthologous to human RAC2 (Rac family small GTPase 2). [provided by Alliance of Genome Resources, Apr 2022]

Rac2 Products (1)

mRNA Protein Name
NM_001008384.1 NP_001008385.1 ras-related C3 botulinum toxin substrate 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in actin cytoskeleton organization IDA
IDA: Inferred from direct assay
10350213 RGD
involved in bone resorption IDA
IDA: Inferred from direct assay
10350213 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related C3 botulinum toxin substrate 2

  • RAS-related C3 botulinum substrate 2

  • ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16659 EHT 1864 Inhibitor 99.85% Unkown
HY-113849 MLS-573151 Inhibitor 99.66% Unkown
HY-132316S (rac)-2,4-O-Dimethylzearalenone-d6 / Unkown
HY-RS11592 RAC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W051624S (Rac)-2-Aminothiazoline-4-carboxylic acid-13C,15N2 / Unkown
HY-W704952 rac 2-(tert-Butyldimethylsilyloxy) Ibuprofen-d6 / Unkown
HY-W756586 Rac 2-stearoyl-3-chloropropanediol-13C3 / Unkown
HY-W756589 Rac 2-linolenoyl-3-chloropropanediol-13C3 / Unkown
HY-143681S (Rac)-2-Palmitoyl-3-chloropropanediol-d5 / Unkown
HY-RS17270 Rac2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23724 Rac2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W010590S (Rac)-2-Aminobutyric acid-d3 / Unkown
HY-W440982A (Rac)-SOPC / Unkown
HY-W778187 rac 2-Oleoyl-3-chloropropanediol-d5,95% / Unkown
HY-W778189 rac-2-Linoleoyl-3-chloropropanediol-d5,95% / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rac2 NCBI NCBI:5880