Ighe - Immunoglobulin heavy constant epsilon Gene

Also Known as Gm900

Species: Mus musculus

Gene Type: other
Gene ID: 380792

Summary

Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to Other organism; and phagocytosis. Predicted to be part of immunoglobulin complex, circulating. Predicted to be active in external side of plasma membrane. Orthologous to human IGHE (immunoglobulin heavy constant epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in B cell differentiation IGI
IGI: Inferred from genetic interaction
28923960 MGI
involved in B cell differentiation IMP
IMP: Inferred from mutant phenotype
28923960 MGI
involved in immunoglobulin production IMP
IMP: Inferred from mutant phenotype
28923960 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytoplasm IDA
IDA: Inferred from direct assay
28923960 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Recombinant Ighe Proteins

Cat. No. Product Name Accession Purity
HY-P77695 IgE Protein, Mouse (HEK293, His) P06336 (V91-S421) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P77696 IgE Protein, Mouse (HEK293, His-Avi) P06336 (D198-S421) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Phase
HY-P99300 Ligelizumab Inhibitor 99.85% Phase 3
HY-P99313 Quilizumab Inducer 99.56% Phase 2
HY-P991256 FB-825 Inhibitor / Phase 2
HY-P991252 XmAb-7195 Inhibitor 99.98% Phase 1

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16358 IGHE Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19398 Ighe Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ighe NCBI NCBI:3497