1. Gene
  2. KIF11 - kinesin family member 11 Gene

KIF11 - kinesin family member 11 Gene

Homo sapiens

Also known as EG5; HKSP; KNSL1; MCLMR; TRIP5

Gene ID: 3832 | Gene type: protein coding

About KIF11

Cytogenetic location: 10q23.33 Genomic coordinates (GRCh38): 10:92,593,130-92,655,395 (from NCBI)

This gene has 5 transcripts (splice variants), 203 orthologues, 41 paralogues and is associated with 4 phenotypes. Broad expression in lymph node (RPKM 9.9), bone marrow (RPKM 8.6) and 18 other tissues.

Summary

This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008]

KIF11 Products(1)

mRNA Protein Name
NM_004523.4 NP_004514.2 kinesin-like protein KIF11

KIF11 Protein Structure

Kinesin

Kinesin: Kinesin motor domain (24 - 359)

Microtub_bind

Microtub_bind: Kinesin-associated microtubule-binding (916 - 1053)

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  • 1056 a.a.
Protein Preferred Names Protein Names

kinesin-like protein KIF11

TR-interacting protein 5

Related Diseases

Diseases Alias
Microcephaly With Or Without Chorioretinopathy, Lymphedema, Or Mental Retardation

Lymphedema, Microcephaly And Chorioretinopathy Syndrome

Microcephaly With Or Without Chorioretinopathy, Lymphedema, Or Intellectual Disability

MCLMR

Microcephaly, Lymphedema, Chorioretinal Dysplasia Syndrome

Mlcrd Syndrome

Cdmmr Syndrome

Lymphedema And Retinal Folds With Microcephaly And Microphthalmos

Chorioretinal Dysplasia-Microcephaly-Mental Retardation Syndrome

Microcephaly Lymphedema Chorioretinal Dysplasia

Microcephaly And Chorioretinopathy With Or Without Mental Retardation, Autosomal Dominant

Lymphedema, Microcephaly, Chorioretinopathy Syndrome

Lymphedema And Retinal Folds With Ficrocephaly And Microphthalmos

Chorioretinal Dysplasia-Microcephaly-Intellectual Disability Syndrome

Microcephaly-Lymphedema-Chorioretinopathy Syndrome

Mlcrd

Lymphedema Microcephaly Chorioretinopathy Syndrome

Microcephaly Lymphedema Chorioretinal Dysplasia Syndrome

Microcephaly With Or Without Chorioretinopathy, Lymphedema Or Intellectual Disability

Microcephaly With/Without Chorioretinopathy, Lymphedema, Or Mental Retardation

Syndromic Rod-Cone Dystrophy

Syndromic Retinitis Pigmentosa

Microcephaly And Chorioretinopathy 1
Microcephaly And Chorioretinopathy, Autosomal Recessive, 1

MCCRP1

Microcephaly And Chorioretinopathy, Autosomal Recessive, Type 1

Chorioretinal Dysplasia-Microcephaly-Mental Retardation Syndrome

Lymphedema, Microcephaly And Chorioretinopathy Syndrome

Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly

Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy

CORD2

Cone-Rod Retinal Dystrophy

Rcrd2

Cone-Rod Retinal Dystrophy 2

Crd2

Cord

Crd

Retinal Cone-Rod Dystrophy

Cone-Rod Retinal Dystrophy-2

Retinal Cone-Rod Dystrophy 2

Tapetoretinal Degeneration

Cone-Rod Degeneration

Cone Rod Dystrophy

Dystrophy, Cone-Rod

Dystrophy, Cone-Rod, Type 2

Retinitis Pigmentosa

Retinitis Pigmentosa 2

Progressive Cone-Rod Dystrophy

Congenital Lymphedema

Lymphedema, Congenital

Milroy Disease

Microcephaly, Autosomal Dominant

Autosomal Dominant Microcephaly

Microcephaly Autosomal Dominant

Autosomal Dominant Primary Microcephaly

Microcephaly With Autosomal Dominant Inheritance

Astigmatism
Invasive Bladder Transitional Cell Carcinoma

Invasive Bladder Urothelial Carcinoma

Infiltrating Bladder Urothelial Carcinoma

Fundus Dystrophy

Retinal Dystrophy

Retinal Dystrophies

Dystrophy, Retinal

Exudative Vitreoretinopathy

Familial Exudative Vitreoretinopathy

Fevr

Criswick-Schepens Syndrome

Exudative Vitreoretinopathy, Familial

Vitreoretinopathy, Exudative )

Exudative Vitreoretinopathy 1

Norrie Disease

Atrophia Bulborum Hereditaria

Episkopi Blindness

Pseudoglioma

ND

Norrie-Warburg Disease

Anderson-Warburg Syndrome

Fetal Iritis Syndrome

Norrie Syndrome

Norrie-Warburg Syndrome

Ndp

Congenital Progressive Oculo-Acoustico-Cerebral Degeneration

Norrie'S Disease

Oligophrenia Microphthalmus

Pseudoglioma Congenita

Whitnall-Norman Syndrome

Microphthalmia

Microphthalmos

Isolated Anophthalmia-Microphthalmia Syndrome

Isolated Microphthalmia-Anophthalmia-Coloboma

Simple Microphthalmos

Clinical Anophthalmia

Isolated Anophthalmia - Microphthalmia

Isolated Pure Microphthalmia

Mac Spectrum

Microphthalmia-Anophthalmia-Coloboma Spectrum

Primitive Anophthalmia

Globe Of Eye Small

Small Eyeball

Hypoplasia Of Eye

Isolated Nanophthalmos

Rudimentary Eye

Dysplasia Of Eye

Primary Autosomal Recessive Microcephaly

Autosomal Recessive Primary Microcephaly

Mcph

True Microcephaly

Microcephalia Vera

Microcephaly Vera

Microcephaly Primary Hereditary

Microcephaly, Primary, Autosomal Recessive

Primary Microcephaly

Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris KIF11 VGNC VGNC:42379
Rattus norvegicus KIF11 RGD RGD:621258
Macaca mulatta KIF11 VGNC VGNC:74030
Bos taurus KIF11 VGNC VGNC:30580
Mus musculus KIF11 MGD MGI:1098231
Felis catus KIF11 VGNC VGNC:67971
Others KIF11 NCBI