TBC1D3B - TBC1 domain family member 3B Gene

Homo sapiens

Also known as PRC17; TBC1D3I; TBC1D3L

Gene ID: 414059 | Gene type: protein coding

About TBC1D3B

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:36,165,683-36,176,636 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 21 orthologues and 45 paralogues. Broad expression in testis (RPKM 19.5), skin (RPKM 8.9) and 23 other tissues.

Summary

This gene encodes a protein that is similar to TBC1 domain family, member 3. This protein contains a TBC (Tre-2, Bub2p, and Cdc16p) domain, which is found in proteins involved in RAB GTPase signaling and vesicle trafficking. There are multiple copies of this gene located within a cluster of chemokine genes on chromosome 17q. [provided by RefSeq, Apr 2009]

TBC1D3B Products(1)

mRNA	Protein	Name
NM_001001417.7	NP_001001417.6	TBC1 domain family member 3B

TBC1D3B Protein Structure

RabGAP-TBC

0
100
200
300
400
500
549 a.a.

Protein Preferred Names

Protein Names

TBC1 domain family member 3B

Rab GTPase-activating protein PRC17 duplicate

Related Diseases

Diseases

Alias

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14243	TBC1D3B Human Pre-designed siRNA Set A		/	Unkown

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