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TBC1D3B - TBC1 domain family member 3B Gene

Also Known as PRC17; TBC1D3I; TBC1D3L

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 414059

About TBC1D3B

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:36,165,683-36,176,636 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 21 orthologues and 45 paralogues. Broad expression in testis (RPKM 19.5), skin (RPKM 8.9) and 23 other tissues.

Summary

This gene encodes a protein that is similar to TBC1 domain family, member 3. This protein contains a TBC (Tre-2, Bub2p, and Cdc16p) domain, which is found in proteins involved in RAB GTPase signaling and vesicle trafficking. There are multiple copies of this gene located within a cluster of chemokine genes on chromosome 17q. [provided by RefSeq, Apr 2009]

TBC1D3B Products (1)

mRNA	Protein	Name
NM_001001417.7	NP_001001417.6	TBC1 domain family member 3B

TBC1D3B Protein Structure

RabGAP-TBC

0
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300
400
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549 a.a.

Protein Preferred Names	Protein Names
TBC1 domain family member 3B	Rab GTPase-activating protein PRC17 duplicate

Related Diseases

Diseases	Alias
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14243	TBC1D3B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown