ART1 - ADP-ribosyltransferase 1 Gene

Also Known as RT6; ART2; ARTC1; CD296

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 417

About ART1

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:3,645,128-3,664,416 (from NCBI)

This gene has 2 transcripts (splice variants), 652 orthologues and 3 paralogues. Low expression observed in reference dataset.

Summary

ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of Bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008]

ART1 Products (1)

mRNA Protein Name
NM_004314.3 NP_004305.2 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 precursor

ART1 Protein Structure

ART

ART: NAD:arginine ADP-ribosyltransferase (39 - 274)

  • 0
  • 100
  • 200
  • 300
  • 327 a.a.
Protein Preferred Names Protein Names

GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1

  • ADP-ribosyltransferase 2

Related Diseases

Diseases Alias
Type 1 Diabetes Mellitus 8

  • Diabetes Mellitus, Insulin-Dependent, 8

  • Iddm8

  • Insulin-Dependent Diabetes Mellitus 8

  • T1D8

  • Insulin-Dependent Diabetes Mellitus-8
Lutembacher'S Syndrome

  • Lutembacher Syndrome

  • Lutembacher'S Anomaly
Lateral Myocardial Infarction
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01044 ART1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15168 TSPAN32 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18463 Art1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24944 Art1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ART1 MGD MGI:107511
Felis catus ART1 VGNC VGNC:68316
Canis familiaris ART1 VGNC VGNC:38147
Rattus norvegicus ART1 RGD RGD:1304591
Macaca mulatta ART1 VGNC VGNC:70024
Others ART1 NCBI