UNC13C - unc-13 homolog C Gene

Homo sapiens

Gene ID: 440279 | Gene type: protein coding

About UNC13C

Cytogenetic location: 15q21.3 Genomic coordinates (GRCh38): 15:53,837,602-54,633,440 (from NCBI)

This gene has 6 transcripts (splice variants), 218 orthologues and 2 paralogues. Biased expression in brain (RPKM 3.2), thyroid (RPKM 0.4) and 4 other tissues.

Summary

Predicted to enable Calmodulin binding activity and syntaxin-1 binding activity. Predicted to be involved in several processes, including glutamatergic synaptic transmission; regulated exocytosis; and synaptic vesicle maturation. Predicted to be located in presynaptic active zone. Predicted to be active in several cellular components, including axon terminus; parallel fiber to Purkinje cell synapse; and presynaptic active zone cytoplasmic component. [provided by Alliance of Genome Resources, Apr 2022]

UNC13C Products(2)

mRNA	Protein	Name
NM_001080534.3	NP_001074003.1	protein unc-13 homolog C isoform 1
NM_001329919.2	NP_001316848.1	protein unc-13 homolog C isoform 2

UNC13C Protein Structure

C1_1

DUF1041

Membr_traf_MHD

0
400
800
1200
1600
2000
2214 a.a.

Protein Preferred Names

Protein Names

protein unc-13 homolog C

Munc13-3

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15466	UNC13C Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	UNC13C	VGNC	VGNC:36665
Mus musculus	UNC13C	MGD	MGI:2149021
Canis familiaris	UNC13C	VGNC	VGNC:48135
Felis catus	UNC13C	VGNC	VGNC:66823
Macaca mulatta	UNC13C	VGNC	VGNC:99340
Rattus norvegicus	UNC13C	RGD	RGD:628592

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