MTX1 - metaxin 1 Gene

Homo sapiens

Also known as MTX; MTXN

Gene ID: 4580 | Gene type: protein coding

About MTX1

Cytogenetic location: 1q22 Genomic coordinates (GRCh38): 1:155,208,695-155,213,839 (from NCBI)

This gene has 7 transcripts (splice variants), 210 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 23.1), bone marrow (RPKM 13.8) and 25 other tissues.

Summary

Predicted to be involved in mitochondrion organization. Part of MIB complex and SAM complex. [provided by Alliance of Genome Resources, Apr 2022]

MTX1 Products(2)

mRNA	Protein	Name
NM_002455.5	NP_002446.3	metaxin-1 isoform 1
NM_198883.3	NP_942584.2	metaxin-1 isoform 2

MTX1 Protein Structure

Tom37

Tom37_C

GST_C_2

0
100
200
300
400
466 a.a.

Protein Preferred Names

Protein Names

metaxin-1

mitochondrial outer membrane import complex protein 1

Related Diseases

Diseases

Alias

Gaucher'S Disease

Gaucher Disease	Kerasin Thesaurismosis
Glucocerebrosidase Deficiency	Glucosylceramidase Deficiency
Cerebroside Lipidosis Syndrome	Acid Beta-Glucosidase Deficiency
Glucosylceramide Beta-Glucosidase Deficiency	Acute Cerebral Gaucher Disease
Gaucher Splenomegaly	Glucocerebrosidosis
Glucosyl Cerebroside Lipidosis	Kerasin Lipoidosis
Lipoid Histiocytosis	Glocucerebrosidase Deficiency
Sphingolipidosis 1	Gaucher Syndrome
Gauchers Disease	Gd
Glucosylceramide Lipidosis	Kerasin Histiocytosis
Gaucher Disease, Type 1	Gaucher Disease, Type 2

Non-Syndromic X-Linked Intellectual Disability 1

Mrx1	Mrx18
Mrx78	X-Linked Mental Retardation 1/78
X-Linked Mental Retardation 18

Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability	Non-Specific X-Linked Mental Retardation
X-Linked Non-Specific Intellectual Disability

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08828	MTX1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	MTX1	VGNC	VGNC:53621
Bos taurus	MTX1	VGNC	VGNC:55630
Mus musculus	MTX1	MGD	MGI:103025
Rattus norvegicus	MTX1	RGD	RGD:1559791