SCN1A - sodium voltage-gated channel alpha subunit 1 Gene
Species: Canis lupus familiaris (sub-species: familiaris)
Gene Type: protein coding
Gene ID: 478775
About SCN1A
Primary_assembly 36: 11,240,401-11,380,345 reverse strand.ROS_Cfam_1.0:CM025135.1
This gene has 4 transcripts (splice variants), 140 orthologues and 27 paralogues.
SCN1A Products (6)
| mRNA | Protein | Name |
|---|---|---|
| XM_038446937.1 | XP_038302865.1 | sodium channel protein type 1 subunit alpha isoform X1 |
| XM_038446941.1 | XP_038302869.1 | sodium channel protein type 1 subunit alpha isoform X2 |
| XM_038446938.1 | XP_038302866.1 | sodium channel protein type 1 subunit alpha isoform X1 |
| XM_038446939.1 | XP_038302867.1 | sodium channel protein type 1 subunit alpha isoform X1 |
| XM_038446942.1 | XP_038302870.1 | sodium channel protein type 1 subunit alpha isoform X3 |
| XM_038446940.1 | XP_038302868.1 | sodium channel protein type 1 subunit alpha isoform X1 |
SCN1A Protein Structure
Ion_trans
Ion_trans: pfam00520 (126 - 432)
Na_trans_cytopl
Na_trans_cytopl: pfam11933 (554 - 717)
Ion_trans
Ion_trans: pfam00520 (766 - 979)
Na_trans_assoc
Na_trans_assoc: pfam06512 (1005 - 1212)
Ion_trans
Ion_trans: pfam00520 (1216 - 1491)
Na_channel_gate
Na_channel_gate: cd13433 (1483 - 1535)
Ion_trans
Ion_trans: pfam00520 (1539 - 1795)
- 0
- 400
- 800
- 1200
- 1600
- 2009 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sodium channel protein type 1 subunit alpha LOW QUALITY PROTEIN: sodium channel protein type 1 subunit alpha |
|
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-148410A | Zorevunersen sodium | Activator | 99.27% | Phase 3 |
| HY-148410 | Zorevunersen | Activator | 98.50% | Phase 3 |
Pre-clinical Phase
Bioactive Molecules
(6)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-125928 | AA43279 | Inhibitor | 99.80% | Unkown |
| HY-148410C | Zorevunensen negative control | Activator | 99.28% | Unkown |
| HY-181575 | TPH2 agonist-1 | Inhibitor | / | Unkown |
| HY-RS12525 | SCN1A Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS12526 | Scn1a Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS12527 | SCN1A Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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