Grb10 - growth factor receptor bound protein 10 Gene

Also Known as RGD1566234

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 498416

Summary

Enables Insulin Receptor binding activity. Involved in Insulin Receptor signaling pathway; negative regulation of glycogen biosynthetic process; and positive regulation of phosphorylation. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Orthologous to human GRB10 (growth factor receptor bound protein 10). [provided by Alliance of Genome Resources, Apr 2022]

Grb10 Products (2)

mRNA Protein Name
NM_001401403.1 NP_001388332.1 growth factor receptor-bound protein 10 isoform 1
NM_001401404.1 NP_001388333.1 growth factor receptor-bound protein 10 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables insulin receptor binding IDA
IDA: Inferred from direct assay
11223174 RGD
Biological Process GO Annotation Evidence References Source
involved in insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
11223174 RGD
involved in negative regulation of glycogen biosynthetic process IDA
IDA: Inferred from direct assay
11223174 RGD
involved in positive regulation of phosphorylation IDA
IDA: Inferred from direct assay
11223174 RGD
involved in response to insulin IDA
IDA: Inferred from direct assay
11223174 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth factor receptor-bound protein 10

  • GRB10 adapter protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05778 GRB10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22539 Grb10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29059 Grb10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grb10 NCBI NCBI:2887