Ucn3 - urocortin 3 Gene

Also Known as RGD1562213

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 498791

Summary

Predicted to enable corticotropin-releasing hormone receptor binding activity. Involved in several processes, including positive regulation of Insulin secretion; positive regulation of membrane potential; and response to corticosterone. Located in axon terminus and varicosity. Orthologous to human UCN3 (urocortin 3). [provided by Alliance of Genome Resources, Apr 2022]

Ucn3 Products (1)

mRNA Protein Name
NM_001080208.2 NP_001073677.1 urocortin-3 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
14519439 RGD
involved in cellular response to nutrient levels IEP
IEP: Inferred from expression pattern
17360501 RGD
involved in positive regulation of insulin secretion IMP
IMP: Inferred from mutant phenotype
17360501 RGD
involved in positive regulation of membrane potential IDA
IDA: Inferred from direct assay
18635602 RGD
involved in response to corticosterone IEP
IEP: Inferred from expression pattern
16809443 RGD
involved in response to glucose IEP
IEP: Inferred from expression pattern
17360501 RGD
involved in response to immobilization stress IEP
IEP: Inferred from expression pattern
16809443 RGD
involved in response to starvation IEP
IEP: Inferred from expression pattern
16809443 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
11826127 RGD
located in axon terminus IDA
IDA: Inferred from direct assay
21452217 RGD
located in varicosity IDA
IDA: Inferred from direct assay
11826127 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

urocortin-3

  • urocortin 3 (stresscopin)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1858A Urocortin III, mouse TFA Activator 98.06% Unkown
HY-P1858 Urocortin III, mouse Activator 98.29% Unkown
HY-RS15409 UCN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21451 Ucn3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27969 Ucn3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ucn3 NCBI NCBI:114131