Thop1 - thimet oligopeptidase 1 Gene

Also Known as EP24.15

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50492

Summary

Enables metalloendopeptidase activity. Acts upstream of or within intracellular signal transduction and peptide metabolic process. Predicted to be located in cytoplasm. Predicted to be active in mitochondrial intermembrane space. Is expressed in head mesenchyme and vertebral axis musculature. Orthologous to human THOP1 (thimet oligopeptidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Thop1 Products (1)

mRNA Protein Name
NM_022653.4 NP_073144.3 thimet oligopeptidase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables metalloendopeptidase activity IDA
IDA: Inferred from direct assay
10969067 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within intracellular signal transduction IDA
IDA: Inferred from direct assay
10969067 MGI
acts upstream of or within peptide metabolic process IDA
IDA: Inferred from direct assay
10969067 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thimet oligopeptidase

  • endopeptidase 24.15

Recombinant Thop1 Proteins

Cat. No. Product Name Accession Purity
HY-P77230 THOP1 Protein, Mouse (sf9, His) Q8C1A5 (K2-C687) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14497 THOP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19241 Thop1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25730 Thop1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Thop1 NCBI NCBI:7064