Rab10 - RAB10, member RAS oncogene family Gene

Also Known as Ac1075

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 50993

Summary

Enables GDP-dissociation inhibitor binding activity and Myosin V binding activity. Involved in Golgi to plasma membrane transport; cellular response to antibiotic; and generation of neurons. Located in several cellular components, including cilium; perinuclear region of cytoplasm; and trans-Golgi network. Is anchored component of synaptic vesicle membrane. Orthologous to human RAB10 (RAB10, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab10 Products (1)

mRNA Protein Name
NM_017359.2 NP_059055.2 ras-related protein Rab-10

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GDP-dissociation inhibitor binding IPI
IPI: Inferred from physical interaction
21856246 RGD
enables myosin V binding IPI
IPI: Inferred from physical interaction
23770993 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
21856246 RGD
Biological Process GO Annotation Evidence References Source
involved in Golgi to plasma membrane transport IMP
IMP: Inferred from mutant phenotype
21856246 RGD
involved in axonogenesis IMP
IMP: Inferred from mutant phenotype
21856246 RGD
involved in cellular response to antibiotic IEP
IEP: Inferred from expression pattern
7688123 RGD
involved in establishment of neuroblast polarity IMP
IMP: Inferred from mutant phenotype
21856246 RGD
Cellular Component GO Annotation Evidence References Source
located in cilium IDA
IDA: Inferred from direct assay
20576682 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
7688123 RGD
is active in synaptic vesicle membrane EXP
EXP: Inferred from Experiment
20926670 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
20926670 RGD
is active in synaptic vesicle membrane IMP
IMP: Inferred from mutant phenotype
20926670 RGD
located in trans-Golgi network IDA
IDA: Inferred from direct assay
7688123 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-10

  • ras-related protein rab10

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148030 XL01126 98.90% Unkown
HY-RS11514 RAB10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21710 Rab10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-180320 Lu AF58786 Inhibitor / Unkown
HY-184198 LRRK2-IN-22 Inhibitor / Unkown
HY-RS28228 Rab10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab10 NCBI NCBI:10890