1. Gene
  2. HIGD1B - HIG1 hypoxia inducible domain family member 1B Gene

HIGD1B - HIG1 hypoxia inducible domain family member 1B Gene

Homo sapiens

Also known as CLST11240; CLST11240-15

Gene ID: 51751 | Gene type: protein coding

About HIGD1B

This gene has 5 transcripts (splice variants), 105 orthologues and 4 paralogues. Biased expression in placenta (RPKM 9.3), lung (RPKM 4.3) and 9 other tissues.

Summary

This gene encodes a member of the hypoxia inducible gene 1 (HIG1) domain family. The encoded protein is localized to the cell membrane and has been linked to tumorigenesis and the progression of pituitary adenomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

HIGD1B Products(2)

mRNA Protein Name
NM_001271880.2 NP_001258809.1 HIG1 domain family member 1B
NM_016438.4 NP_057522.1 HIG1 domain family member 1B

HIGD1B Protein Structure

HIG_1_N

HIG_1_N: Hypoxia induced protein conserved region (26 - 79)

  • 0
  • 99 a.a.
Protein Preferred Names Protein Names

HIG1 domain family member 1B

Related Diseases

Diseases Alias
Trachea Adenoid Cystic Carcinoma

Tracheal Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma Of Trachea

Tracheal Cancer

Tracheal Carcinoma

Malignant Neoplasm Of Trachea

Tracheal Neoplasms

Pancoast Tumor

Pulmonary Sulcus Neoplasm

Pancoast Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris HIGD1B VGNC VGNC:41688
Bos taurus HIGD1B VGNC VGNC:29851
Macaca mulatta HIGD1B VGNC VGNC:104616
Rattus norvegicus HIGD1B RGD RGD:1306907
Felis catus HIGD1B VGNC VGNC:62815
Mus musculus HIGD1B MGD MGI:1922939