Kat6b - K(lysine) acetyltransferase 6B Gene

Also Known as qkf; Morf; Myst4; MYST-4; querkopf; mKIAA0383; B130044K16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54169

Summary

Enables Histone Acetyltransferase activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor and histone acetylation. Predicted to be located in nucleus. Predicted to be part of MOZ/MORF Histone Acetyltransferase complex. Is expressed in several structures, including brain; early conceptus; facial prominence; genitourinary system; and limb mesenchyme. Used to study Noonan syndrome. Human ortholog(s) of this gene implicated in bipolar disorder; blepharophimosis-intellectual disability syndrome, SBBYS type; breast cancer; and leiomyoma. Orthologous to human KAT6B (lysine acetyltransferase 6B). [provided by Alliance of Genome Resources, Apr 2022]

Kat6b Products (4)

mRNA Protein Name
NM_001205241.2 NP_001192170.1 histone acetyltransferase KAT6B isoform 1
NM_001408695.1 NP_001395624.1 histone acetyltransferase KAT6B isoform 1
NM_001408696.1 NP_001395625.1 histone acetyltransferase KAT6B isoform 2
NM_017479.4 NP_059507.2 histone acetyltransferase KAT6B isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables histone acetyltransferase activity IDA
IDA: Inferred from direct assay
10821753 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone acetyltransferase KAT6B

  • MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4

  • MYST histone acetyltransferase monocytic leukemia 4

  • histone acetyltransferase MYST4

  • histone acetyltransferase querkopf

  • monocytic leukemia

  • protein querkopf

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-132283 PF-9363 Inhibitor 99.64% Unkown
HY-159957 BAY-184 Inhibitor 99.00% Unkown
HY-162997 KAT6-IN-3 Inhibitor / Unkown
HY-183256 BAY-7728 Inhibitor / Unkown
HY-RS07082 KAT6B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22583 Kat6b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29100 Kat6b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kat6b NCBI NCBI:23522