Cfd - complement factor D Gene

Also Known as Df; Adn; EVE

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 54249

Summary

Enables endopeptidase activity. Involved in Notch signaling pathway. Located in extracellular space. Used to study arthus reaction. Biomarker of obesity. Orthologous to human CFD (complement Factor D). [provided by Alliance of Genome Resources, Apr 2022]

Cfd Products (1)

mRNA Protein Name
NM_001077642.1 NP_001071110.1 complement factor D precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables endopeptidase activity IDA
IDA: Inferred from direct assay
1953671 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in Notch signaling pathway IMP
IMP: Inferred from mutant phenotype
12949072 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in extracellular space IDA
IDA: Inferred from direct assay
2197880 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement factor D

  • C3 convertase activator

  • D component of complement (adipsin)

  • adipsin

  • endogenous vascular elastase

  • properdin factor D

Recombinant Cfd Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P71726 Complement Factor D/Adipsin Protein, Rat (P.pastoris, His) P32038 (I26-A263) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Art. -Nr. Produktname Wirkung
Reinheit Phase
HY-P99298 Lampalizumab Inhibitor 99.46% Phase 3

Pre-clinical Phase

Bioactive Molecules (5)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-163684 Zoracopan Inhibitor 99.85% Unkown
HY-RS02559 CFD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10542 PIKFYVE Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17155 Cfd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23605 Cfd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cfd NCBI NCBI:1675