Elovl1 - elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 Gene

Also Known as Ssc1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54325

Summary

Predicted to enable fatty acid elongase activity. Involved in ceramide biosynthetic process and establishment of skin barrier. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in brain; epidermis; epidermis stratum granulosum; epidermis stratum spinosum; and skin. Orthologous to human ELOVL1 (ELOVL fatty acid elongase 1). [provided by Alliance of Genome Resources, Apr 2022]

Elovl1 Products (3)

mRNA Protein Name
NM_001039175.2 NP_001034264.1 elongation of very long chain fatty acids protein 1 isoform 2
NM_001039176.2 NP_001034265.1 elongation of very long chain fatty acids protein 1 isoform 1
NM_019422.3 NP_062295.1 elongation of very long chain fatty acids protein 1 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in ceramide biosynthetic process IMP
IMP: Inferred from mutant phenotype
23689133 MGI
involved in establishment of skin barrier IMP
IMP: Inferred from mutant phenotype
23689133 MGI
involved in sphingolipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
20253178 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

elongation of very long chain fatty acids protein 1

  • 3-keto acyl-CoA synthase Elovl1

  • ELOVL FA elongase 1

  • ELOVL fatty acid elongase 1

  • sequence similarity to Cig30 1

  • very long chain 3-ketoacyl-CoA synthase 1

  • very long chain 3-oxoacyl-CoA synthase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W269593 Perfluorodecanoic acid Inhibitor 98.0% Unkown
HY-NP0204 MSA Protein 98% Unkown
HY-145272 ELOVL1-IN-3 99.93% Unkown
HY-152947 ELOVL6-IN-4 98.94% Unkown
HY-145122 ELOVL1-IN-1 98.02% Unkown
HY-160912 ELOVL6-IN-5 Inhibitor 95.47% Unkown
HY-145270 ELOVL1-IN-2 99.82% Unkown
HY-RS04321 ELOVL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18862 Elovl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25354 Elovl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elovl1 NCBI NCBI:64834