Elovl2 - elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 Gene

Also Known as Ssc2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54326

Summary

Enables fatty acid elongase activity. Involved in fatty acid elongation, polyunsaturated fatty acid and very long-chain fatty acid biosynthetic process. Acts upstream of or within very long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including brain; liver; paravertebral ganglion; sensory organ; and urinary system. Orthologous to human ELOVL2 (ELOVL fatty acid elongase 2). [provided by Alliance of Genome Resources, Apr 2022]

Elovl2 Products (2)

mRNA Protein Name
NM_001311121.1 NP_001298050.1 elongation of very long chain fatty acids protein 2 isoform 2
NM_019423.2 NP_062296.1 elongation of very long chain fatty acids protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables acyltransferase activity, transferring groups other than amino-acyl groups IDA
IDA: Inferred from direct assay
11567032 MGI
enables fatty acid elongase activity IDA
IDA: Inferred from direct assay
12371743 MGI
Biological Process GO Annotation Evidence References Source
involved in fatty acid elongation, polyunsaturated fatty acid IDA
IDA: Inferred from direct assay
12371743 MGI
involved in fatty acid elongation, polyunsaturated fatty acid IMP
IMP: Inferred from mutant phenotype
21106902 MGI
involved in very long-chain fatty acid biosynthetic process IDA
IDA: Inferred from direct assay
12371743 MGI
involved in very long-chain fatty acid biosynthetic process IMP
IMP: Inferred from mutant phenotype
21106902 MGI
acts upstream of or within very long-chain fatty acid metabolic process IDA
IDA: Inferred from direct assay
11567032 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

elongation of very long chain fatty acids protein 2

  • 3-keto acyl-CoA synthase Elovl2

  • ELOVL FA elongase 2

  • ELOVL family member 2

  • ELOVL fatty acid elongase 2

  • sequence similarity to Cig30 2

  • very long chain 3-ketoacyl-CoA synthase 2

  • very long chain 3-oxoacyl-CoA synthase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS21122 Elovl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04322 ELOVL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27641 Elovl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elovl2 NCBI NCBI:54898