RBM27 - RNA binding motif protein 27 Gene

Also Known as Psc1; ARRS1; ZC3H18; ZC3H20

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54439

About RBM27

Cytogenetic location: 5q32 Genomic coordinates (GRCh38): 5:146,203,605-146,289,223 (from NCBI)

This gene has 2 transcripts (splice variants), 206 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 10.3), bone marrow (RPKM 8.5) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in mRNA processing. Predicted to be located in cytoplasm and nuclear speck. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RBM27 Products (1)

mRNA Protein Name
NM_018989.2 NP_061862.1 RNA-binding protein 27

RBM27 Protein Structure

PWI

PWI: PWI domain (7 - 73)

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (277 - 299)

RRM_5

RRM_5: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (617 - 672)

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  • 1060 a.a.
Protein Preferred Names Protein Names

RNA-binding protein 27

  • acidic rich RS domain containing 1

Related Diseases

Diseases Alias
Osteogenesis Imperfecta, Type Xv
  • Osteogenesis Imperfecta Type 15

  • OI15

  • Osteogenesis Imperfecta Type Xv

  • Oi, Type Xv

  • Osteogenesis Imperfecta 15

  • Oi Type Xv

  • Oi-Xv

Brachydactyly, Type B1
  • Brachydactyly Type B1

  • Brachydactyly Type B

  • BDB1

  • Brachydactyly, Type B

  • Bdb

  • Brachydactyly B1

Osteopetrosis, Autosomal Dominant 1
  • OPTA1

  • Autosomal Dominant Osteopetrosis 1

  • Autosomal Dominant Osteopetrosis Type 1

  • Osteopetrosis Autosomal Dominant Type 1

  • Osteopetrosis, Autosomal Dominant, Type I

  • Osteopetrosis, Autosomal Dominant, Type 1

Robinow Syndrome, Autosomal Recessive 1
  • Robinow Syndrome, Autosomal Recessive

  • Autosomal Recessive Robinow Syndrome

  • Covesdem Syndrome

  • RRS1

  • Costovertebral Segmentation Defect-Mesomelia Syndrome

  • Rrs

  • Costovertebral Segmentation Defect With Mesomelia, Formerly

  • Covesdem Syndrome, Formerly

  • Costovertebral Segmentation Defect With Mesomelia

  • Robinow Syndrome Autosomal Recessive With Aplasia/Hypoplasia Of Phalanges And Metacarpals/Metatarsals

  • Robinow Syndrome Autosomal Recessive With Brachy-Syn-Polydactyly

  • Robinow Syndrome, Autosomal Recessive, With Aplasia/Hypoplasia Of Phalanges And Metacarpals/Metatarsals

  • Robinow Syndrome, Autosomal Recessive, With Brachy-Syn-Polydactyly

  • Robinow, Autosomal Recessive Syndrome, Type 1

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RBM27 RGD RGD:1311966
Mus musculus RBM27 MGD MGI:2147194