Nfat5 - nuclear factor of activated T cells 5 Gene

Also Known as CAG-8; CAG80; OREBP; nfatz; NFATL1; TonEBP; mKIAA0827; B130038B15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54446

Summary

Enables DNA binding activity. Acts upstream of or within positive regulation of gene expression; positive regulation of transcription by RNA polymerase II; and regulation of calcineurin-NFAT signaling cascade. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; endocrine gland; genitourinary system; and midbrain roof plate. Orthologous to human NFAT5 (nuclear factor of activated T cells 5). [provided by Alliance of Genome Resources, Apr 2022]

Nfat5 Products (3)

mRNA Protein Name
NM_001286260.1 NP_001273189.1 nuclear factor of activated T-cells 5 isoform c
NM_018823.2 NP_061293.2 nuclear factor of activated T-cells 5 isoform b
NM_133957.3 NP_598718.2 nuclear factor of activated T-cells 5 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
15790681 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cytokine production IDA
IDA: Inferred from direct assay
15790681 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: Inferred from direct assay
21357543 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11934689 MGI
acts upstream of or within regulation of calcineurin-NFAT signaling cascade IDA
IDA: Inferred from direct assay
19188439 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11934689 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10860829 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear factor of activated T-cells 5

  • T-cell transcription factor NFAT5

  • rel domain-containing transcription factor NFAT5

  • tonicity-responsive enhancer binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112125A KRN2 bromide 98.81% Unkown
HY-112125 KRN2 98.04% Unkown
HY-112126 KRN5 98.76% Unkown
HY-12117 L-NIL hydrochloride Inhibitor / Unkown
HY-RS09237 NFAT5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17610 Nfat5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24070 Nfat5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfat5 NCBI NCBI:10725