DCAF16 - DDB1 and CUL4 associated factor 16 Gene

Also Known as C4orf30

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54876

About DCAF16

This gene has 3 transcripts (splice variants) and 64 orthologues. Ubiquitous expression in ovary (RPKM 5.2), endometrium (RPKM 5.1) and 25 other tissues.

Summary

Predicted to be involved in protein ubiquitination. Part of Cul4-RING E3 ubiquitin Ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

DCAF16 Products (6)

mRNA Protein Name
NM_001345880.2 NP_001332809.1 DDB1- and CUL4-associated factor 16
NM_001345881.2 NP_001332810.1 DDB1- and CUL4-associated factor 16
NM_001345882.2 NP_001332811.1 DDB1- and CUL4-associated factor 16
NM_001345884.2 NP_001332813.1 DDB1- and CUL4-associated factor 16
NM_001345885.2 NP_001332814.1 DDB1- and CUL4-associated factor 16
NM_017741.4 NP_060211.3 DDB1- and CUL4-associated factor 16

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16949367 GOA
Cellular Component GO Annotation Evidence References Source
part of Cul4-RING E3 ubiquitin ligase complex IDA
IDA: Inferred from direct assay
16949367 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DCAF16 Protein Structure

DCA16

DCA16: DDB1- and CUL4-associated factor 16 (1 - 216)

  • 0
  • 100
  • 200
  • 216 a.a.
Protein Preferred Names Protein Names

DDB1- and CUL4-associated factor 16

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (27)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-160528 IBG3 Inhibitor 98.53% Unkown
HY-153385 TMX1 Degrader 99.57% Unkown
HY-156828 MMH2 Degrader 98.95% Unkown
HY-163638 BRD4 degrader-1 Degrader 99.85% Unkown
HY-129917 KB02-JQ1 Inhibitor 99.10% Unkown
HY-129610 KB02-SLF Inhibitor 99.25% Unkown
HY-156827 MMH1 Degrader 99.83% Unkown
HY-172615 AMPTX-1 Degrader 98.00% Unkown
HY-W005799 E3 ligase Ligand 80 / Unkown
HY-183013 PROTAC PARP2 degrader-1 95.86% Unkown
HY-175187 LO-3-63 Degrader 98.16% Unkown
HY-157591 MMH1-NR Control 99.36% Unkown
HY-157592 MMH2-NR Control 98.72% Unkown
HY-182766 AMX-883 Degrader / Unkown
HY-147196 KB03-SLF Degrader / Unkown
HY-163641 AR Degrader-1 Degrader / Unkown
HY-169968 E3 ligase Ligand 41 / Unkown
HY-170983 MC-25B Degrader / Unkown
HY-175179 LO-3-61 Degrader / Unkown
HY-175186 LO-3-62 Degrader / Unkown
HY-175756 SMARCA2/4 degrader-1 Degrader / Unkown
HY-176067 LO-4-25 Degrader / Unkown
HY-183575 JQ1-JX5 Degrader / Unkown
HY-184321 LC-MG-5 / Unkown
HY-RS03562 DCAF16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-176070 HRG038 Inhibitor / Unkown
HY-RS23600 Dcaf16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus DCAF16 VGNC VGNC:61357
Bos taurus DCAF16 VGNC VGNC:27903
Rattus norvegicus DCAF16 RGD RGD:7661830
Macaca mulatta DCAF16 VGNC VGNC:71713
Others DCAF16 NCBI