E3 ligase Ligand 80
Based on 1 Customer Validation
E3 ligase Ligand 80 (Compound S4) is an E3 ligase ligand that can be used in the recruitment of DCAF16 protein. E3 ligase Ligand 80 can be used to synthesis of PROTAC BRD4 degrader JQ1-JX5 (HY-183575).
For research use only. We do not sell to patients.
- CAS No.: 939-69-5
- Formula: C8H4N2OS
- Molecular Weight:176.20
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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DCAF16 |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 939-69-5
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Appearance Solid
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Molecular Weight 176.20
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Formula C8H4N2OS
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SMILES
N#CC1=NC2=C(S1)C=C(O)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
E3 ligase Ligand 80 Related Classifications
HY-W005799 Related Classifications
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