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  3. PPP2R2C - protein phosphatase 2 regulatory subunit Bgamma Gene

PPP2R2C - protein phosphatase 2 regulatory subunit Bgamma Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PR52; PR55G; IMYPNO; IMYPNO1; B55gamma; B55-GAMMA

Gene ID: 5522 | Gene type: protein coding

About PPP2R2C

Cytogenetic location: 4p16.1 Genomic coordinates (GRCh38): 4:6,320,581-6,563,799 (from NCBI)

This gene has 9 transcripts (splice variants), 237 orthologues and 3 paralogues. Biased expression in brain (RPKM 39.0), endometrium (RPKM 11.7) and 4 other tissues.

Summary

The product of this gene belongs to the Phosphatase 2 regulatory subunit B family. Protein Phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core Enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

PPP2R2C Products(6)

mRNA Protein Name
NM_001206994.2 NP_001193923.1 protein phosphatase 2, regulatory subunit B, gamma isoform c
NM_001206995.2 NP_001193924.1 protein phosphatase 2, regulatory subunit B, gamma isoform c
NM_001206996.2 NP_001193925.1 protein phosphatase 2, regulatory subunit B, gamma isoform d
NM_001363388.2 NP_001350317.1 protein phosphatase 2, regulatory subunit B, gamma isoform e
NM_020416.4 NP_065149.2 protein phosphatase 2, regulatory subunit B, gamma isoform a
NM_181876.3 NP_870991.1 protein phosphatase 2, regulatory subunit B, gamma isoform b
Protein Preferred Names Protein Names

protein phosphatase 2, regulatory subunit B, gamma

phosphoprotein phosphatase 2A BR gamma regulatory chain

Related Diseases

Diseases Alias
Inflammatory Bowel Disease 3

IBD3
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11013 PPP2R2C Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris PPP2R2C VGNC VGNC:44909
Macaca mulatta PPP2R2C VGNC VGNC:76377
Bos taurus PPP2R2C VGNC VGNC:33257
Rattus norvegicus PPP2R2C RGD RGD:620920
Mus musculus PPP2R2C MGD MGI:2442660
Felis catus PPP2R2C VGNC VGNC:69013