PRKACG - protein kinase cAMP-activated catalytic subunit gamma Gene

Also Known as KAPG; PKACg; BDPLT19

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5568

About PRKACG

Cytogenetic location: 9q21.11 Genomic coordinates (GRCh38): 9:69,012,504-69,014,113 (from NCBI)

This gene has 1 transcript (splice variant), 365 orthologues, 5 paralogues and is associated with 2 phenotypes.

Summary

Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008]

PRKACG Products (1)

mRNA Protein Name
NM_002732.4 NP_002723.2 cAMP-dependent protein kinase catalytic subunit gamma
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRKACG Protein Structure

Pkinase

Pkinase: Protein kinase domain (44 - 298)

  • 0
  • 100
  • 200
  • 300
  • 351 a.a.
Protein Preferred Names Protein Names

cAMP-dependent protein kinase catalytic subunit gamma

  • PKA C-gamma

PRKACG Antibodies

Cat. No. Product Name Application Reactivity
HY-P81981 PKA C gamma Antibody (YA1726) WB Human, Mouse, Rat
HY-P81981A PKA C gamma Antibody (YA1726)(PBS only) WB Human, Mouse, Rat

Related Diseases

Diseases Alias
Bleeding Disorder, Platelet-Type, 19
  • Platelet-Type Bleeding Disorder 19

  • BDPLT19

  • Severe Autosomal Recessive Macrothrombocytopenia

  • Bleeding Disorder, Platelet Type 19

Friedreich Ataxia
  • Friedreich Ataxia 1

  • FRDA

  • Friedreich Ataxia With Retained Reflexes

  • Frda1

  • Fa

  • Friedreich'S Ataxia

  • Hereditary Spinal Ataxia

  • Fa1

  • Friedreich'S Tabes

  • Hereditary Spinal Sclerosis

  • Spinocerebellar Ataxia, Friedreich

  • Friedreich Spinocerebellar Ataxia

  • Friedrich'S Ataxia

Stormorken Syndrome
  • Thrombocytopathy, Asplenia, And Miosis

  • Stormorken-Sjaastad-Langslet Syndrome

  • STRMK

  • York Platelet Syndrome

  • Yps

  • Thrombocytopathy, Asplenia And Miosis

  • Thrombocytopathy Asplenia Miosis

  • Thrombocytopathy-Asplenia-Miosis Syndrome

  • Miosis Disorder

Thrombocytopenia-Absent Radius Syndrome
  • Tar Syndrome

  • Radial Aplasia-Thrombocytopenia Syndrome

  • Absent Radii And Thrombocytopenia

  • TAR

  • Chromosome 1q21.1 Deletion Syndrome, 200-Kb

  • Thrombocytopenia Absent Radius Syndrome

  • Thrombocytopenia Absent Radii

  • Chromosome 1q21.1 Deletion Syndrome

  • Thrombocytopenia With Absent Radii Syndrome

  • Radial Aplasia-Amegakaryocytic Thrombocytopenia

Carney Complex Variant
  • Carney Complex

  • Carney Syndrome

  • Carney Complex, Type 1

  • Lamb Syndrome

  • Name Syndrome

  • Myxoma-Spotty Pigmentation-Endocrine Overactivity Syndrome

  • Carney Complex - Trismus - Pseudocamptodactyly Syndrome

  • Carney Complex, Type 2

  • Car

  • Cnc1

  • Carney Myxoma-Endocrine Complex

  • Myxoma - Spotty Pigmentation - Endocrine Overactivity

  • Myxoma, Spotty Pigmentation, And Endocrine Overactivity

  • Lamb - Lentigines, Atrial Myxoma, Mucocutaneous Myoma, Blue Nevus Syndrome

  • Name - Nevi, Atrial Myxoma, Skin Myxoma, Ephelides Syndrome

  • Carney Complex-Trismus-Pseudocamptodactyly Syndrome

  • CACOV

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma