Hsd17b12 - hydroxysteroid (17-beta) dehydrogenase 12 Gene

Also Known as Kik1; KIK-I; 2610510O05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56348

Summary

Enables Collagen binding activity; fibronectin binding activity; and heparin binding activity. Acts upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in extracellular matrix. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). [provided by Alliance of Genome Resources, Apr 2022]

Hsd17b12 Products (1)

mRNA Protein Name
NM_019657.4 NP_062631.1 very-long-chain 3-oxoacyl-CoA reductase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables collagen binding IDA
IDA: Inferred from direct assay
18757743 MGI
enables fibronectin binding IDA
IDA: Inferred from direct assay
18757743 MGI
enables heparin binding IDA
IDA: Inferred from direct assay
18757743 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within extracellular matrix organization IDA
IDA: Inferred from direct assay
18757743 MGI
acts upstream of or within positive regulation of cell-substrate adhesion IDA
IDA: Inferred from direct assay
18757743 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
18757743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

very-long-chain 3-oxoacyl-CoA reductase

  • 17-beta-HSD 12

  • 17-beta-hydroxysteroid dehydrogenase 12

  • 3-ketoacyl-CoA reductase

  • KAR

  • estradiol 17-beta-dehydrogenase 12

  • keratoadhesin

  • keratonectin

  • steroid dehydrogenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06392 HSD17B12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20666 Hsd17b12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27177 Hsd17b12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsd17b12 NCBI NCBI:51144