Gabarap - gamma-aminobutyric acid receptor associated protein Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56486

Summary

Enables microtubule binding activity. Acts upstream of or within microtubule Cytoskeleton organization. Located in several cellular components, including cytoskeleton; smooth endoplasmic reticulum; and sperm midpiece. Part of microtubule associated complex. Is expressed in retina inner plexiform layer and spinal cord. Orthologous to human GABARAP (GABA type A receptor-associated protein). [provided by Alliance of Genome Resources, Apr 2022]

Gabarap Products (1)

mRNA Protein Name
NM_019749.4 NP_062723.1 gamma-aminobutyric acid receptor-associated protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
10899939 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10900017 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within microtubule cytoskeleton organization IDA
IDA: Inferred from direct assay
10899939 MGI
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane EXP
EXP: Inferred from Experiment
33436612 MGI
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
33436612 MGI
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane IMP
IMP: Inferred from mutant phenotype
33436612 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse EXP
EXP: Inferred from Experiment
33436612 MGI
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
33436612 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
33436612 MGI
located in Golgi apparatus IDA
IDA: Inferred from direct assay
11146101 MGI
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
10899939 MGI
located in axoneme IDA
IDA: Inferred from direct assay
24089209 MGI
located in lysosome IDA
IDA: Inferred from direct assay
11146101 MGI
part of microtubule associated complex IDA
IDA: Inferred from direct assay
10899939 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10900017 MGI
located in smooth endoplasmic reticulum IDA
IDA: Inferred from direct assay
11146101 MGI
located in sperm midpiece IDA
IDA: Inferred from direct assay
22033522 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-aminobutyric acid receptor-associated protein

  • GABA-A receptor-associated protein

  • gamma-aminobutyric acid reseptor associated protein

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-16121 CAA-0225 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P5964A K1 peptide TFA Ligand 98.59% Unkown
HY-P11208C mNLS-CPP-WSTF TFA Inhibitor 96.20% Unkown
HY-168347 TH152 Ligand / Unkown
HY-P11208 mNLS-CPP-WSTF Inhibitor / Unkown
HY-P5964 K1 peptide Ligand / Unkown
HY-RS05201 GABARAP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17786 Gabarap Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24253 Gabarap Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gabarap NCBI NCBI:11337