CA10 - carbonic anhydrase 10 Gene

Homo sapiens

Also known as CARPX; CA-RPX; HUCEP-15

Gene ID: 56934 | Gene type: protein coding

About CA10

Cytogenetic location: 17q21.33-q22 Genomic coordinates (GRCh38): 17:51,630,313-52,160,023 (from NCBI)

This gene has 9 transcripts (splice variants), 288 orthologues and 14 paralogues. Biased expression in brain (RPKM 15.3), kidney (RPKM 2.4) and 2 other tissues.

Summary

This gene encodes a protein that belongs to the Carbonic Anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

CA10 Products(3)

mRNA	Protein	Name
NM_001082533.1	NP_001076002.1	carbonic anhydrase-related protein 10 precursor
NM_001082534.2	NP_001076003.1	carbonic anhydrase-related protein 10 precursor
NM_020178.5	NP_064563.1	carbonic anhydrase-related protein 10 precursor

CA10 Protein Structure

Carb_anhydrase

0
100
200
300
328 a.a.

Protein Preferred Names

Protein Names

carbonic anhydrase-related protein 10

CA-RP X

Recombinant CA10 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7724	Carbonic Anhydrase 10 Protein, Human (HEK293, His)	Q9NS85 (Q22-N300)	≥95%
HY-P7725	Carbonic Anhydrase 10 Protein, Human (His)	Q9NS85 (A21-N300)	≥95%
HY-P72864	Carbonic Anhydrase 10 Protein, Human (HEK293 )	Q9NS85 (M1-N300)	≥95%

Related Diseases

Diseases

Alias

Enamel Caries

Primary Dental Caries	Dental Caries Limited To Enamel
Simple Dental Cavity

Chondroblastoma

Chondroblastoma Of Bone

Prostate Calculus

Calculus Of Prostate	Prostatic Lithiasis
Stone Of Prostate	Prostatic Stone
Prostate Calculi	Prostatolithiasis

Root Caries

Cementum Caries

Dental Caries Of Root Surface

Non-Suppurative Otitis Media

Nonsuppurative Otitis Media

Enamel Erosion

Tooth Erosion

Generalized Erosion	Localized Erosion
Generalized Erosions	Erosion, Localized

Dentin Caries

Compound Dental Caries	Dental Caries Extending Into Dentine
Dental Caries Extending Into Dentin

Dental Fluorosis

Mottled Teeth	Intrinsic Enamel Discolouration Of Fluorosis
Mottling Of Enamel	Fluorosis, Dental
Dental Fluorosis, Acquired

Lower Urinary Tract Calculus

Calculus Of Lower Urinary Tract

Seckel Syndrome 1

SCKL1	Nanocephalic Dwarfism
Microcephalic Primordial Dwarfism I	Seckel-Type Dwarfism
Bird-Headed Dwarfism	Sckl
Seckel Syndrome, Type 1	Seckel Syndrome

Aseptic Meningitis

Acute Aseptic Meningitis	Meningitis Aseptic
Meningitis, Aseptic

Subdural Empyema

Empyema, Subdural

Subdural Abscess

Arterial Calcification Of Infancy

Idiopathic Infantile Arterial Calcification	Generalized Arterial Calcification Of Infancy
Iiac	Occlusive Infantile Arteriopathy
Infantile Arteriosclerosis	Gaci
Idiopathic Obliterative Arteriopathy	Generalized Arterial Calcification In Infancy
Arteriopathia Calcificans Infantum	Diffuse Arterial Calcifying Elastopathy Of Infancy
Infantile Calcifying Arteriopathy	Medial Coronary Sclerosis Of Infancy
Coronary Sclerosis, Medial, Of Infancy	Calcification, Arterial, Generalized, Infancy

Teeth Hard Tissue Disease

Osteoporosis

Postmenopausal Osteoporosis	Osteoporosis, Postmenopausal
Bone Mineral Density Quantitative Trait Locus	Bmnd
Osteoporosis, Involutional	Osteoporosis, Susceptibility To
Osteoporosis, Postmenopausal, Susceptibility	Bone Mineral Density Variation Qtl, Osteoporosis
OSTEOP	Involutional Osteoporosis
Senile Osteoporosis	Osteoporosis Postmenopausal
Bone Mineral Density, Quantitative Trait Locus	Osteoporosis, Senile
Idiopathic Osteoporosis	Bone Rarefaction Nos
Type 1 Osteoporosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-132239	5-Bromo-6-chloro-3-indolyl β-D-Galactopyranoside contains ca. 10% Ethyl Acetate		/	Unkown
HY-RS01763	CA10 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CA10	VGNC	VGNC:70486
Rattus norvegicus	CA10	RGD	RGD:2322930
Felis catus	CA10	VGNC	VGNC:60240
Bos taurus	CA10	VGNC	VGNC:26648
Canis familiaris	CA10	VGNC	VGNC:38605
Mus musculus	CA10	MGD	MGI:1919855
Others	CA10	NCBI

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