PLXDC1 - plexin domain containing 1 Gene

Also Known as TEM3; TEM7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57125

About PLXDC1

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:39,063,313-39,152,967 (from NCBI)

This gene has 20 transcripts (splice variants), 252 orthologues and 1 paralogue. Ubiquitous expression in gall bladder (RPKM 7.4), endometrium (RPKM 6.4) and 23 other tissues.

Summary

Predicted to be involved in angiogenesis and spinal cord development. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

PLXDC1 Products (1)

mRNA Protein Name
NM_020405.5 NP_065138.2 plexin domain-containing protein 1 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
15574754 GOA
Cellular Component GO Annotation Evidence Références Source
part of receptor complex IDA
IDA: Inferred from direct assay
23382219 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PLXDC1 Protein Structure

PSI

PSI: Plexin repeat (303 - 347)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500 a.a.
Protein Preferred Names Protein Names

plexin domain-containing protein 1

  • 2410003I07Rik

Recombinant PLXDC1 Proteins

Cat. No. Nom du produit Accession Pureté
HY-P71214 PLXDC1 Protein, Human (HEK293, His) AAH36059.1 (L19-T426) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS10746 PLXDC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20579 Plxdc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27087 Plxdc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris PLXDC1 VGNC VGNC:44716
Mus musculus PLXDC1 MGD MGI:1919574
Macaca mulatta PLXDC1 VGNC VGNC:76087
Rattus norvegicus PLXDC1 RGD RGD:1307496
Felis catus PLXDC1 VGNC VGNC:64250
Bos taurus PLXDC1 VGNC VGNC:33057
Others PLXDC1 NCBI