BRINP2 - BMP/retinoic acid inducible neural specific 2 Gene
Also Known as FAM5B; DBCCR1L2
Species: Homo sapiens
About BRINP2
This gene has 3 transcripts (splice variants), 359 orthologues and 2 paralogues. Biased expression in brain (RPKM 11.7), adrenal (RPKM 4.6) and 1 other tissue.
Summary
Predicted to be involved in cellular response to retinoic acid; negative regulation of mitotic cell cycle; and positive regulation of neuron differentiation. Predicted to be located in extracellular region. Predicted to be active in dendrite; endoplasmic reticulum; and neuronal cell body. Implicated in oral squamous cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022]
BRINP2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_021165.4 | NP_066988.1 | BMP/retinoic acid-inducible neural-specific protein 2 precursor |
BRINP2 Protein Structure
MACPF: MAC/Perforin domain (80 - 171)
- 0
- 200
- 400
- 600
- 783 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
BMP/retinoic acid-inducible neural-specific protein 2 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Spinocerebellar Ataxia 37 |
|
|
| Oral Squamous Cell Carcinoma |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P10927 | BRP | 99.62% | Unkown | |
| HY-P10927A | BRP TFA | / | Unkown | |
| HY-RS01621 | BRINP2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | BRINP2 | RGD | RGD:708419 |
| Canis familiaris | BRINP2 | VGNC | VGNC:38528 |
| Bos taurus | BRINP2 | VGNC | VGNC:58363 |
| Felis catus | BRINP2 | VGNC | VGNC:60175 |
| Macaca mulatta | BRINP2 | VGNC | VGNC:70303 |
| Mus musculus | BRINP2 | MGD | MGI:2443333 |
| Others | BRINP2 | NCBI |
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